NSC 9812
4-nitrophenetole
CAS: 100-29-8
Molecular Formula: C8H9NO3
NSC 9812 - Names and Identifiers
| Name | 4-nitrophenetole |
| Synonyms | NSC 9812 AI3-00233 HSDB 5333 CCRIS 2333 BRN 0972473 4-Nitrophenetol p-Nitrophenetol 4-nitrophenetole p-Nitrophenetole 4-Nitrophenetole Phenetole, p-nitro- 4-Ethoxynitrobenzene p-Ethoxynitrobenzene 1-Ethoxy-4-nitrobenzene p-Nitrophenetol [German] Ethyl p-nitrophenyl ether Phenetole, p-nitro- (8CI) Benzene, 1-ethoxy-4-nitro- 4-06-00-01283 (Beilstein Handbook Reference) |
| CAS | 100-29-8 |
| EINECS | 202-837-9 |
| InChI | InChI=1/C8H9NO3/c1-2-12-8-5-3-7(4-6-8)9(10)11/h3-6H,2H2,1H3 |
NSC 9812 - Physico-chemical Properties
| Molecular Formula | C8H9NO3 |
| Molar Mass | 167.162 |
| Density | 1.178g/cm3 |
| Melting Point | 56-60℃ |
| Boling Point | 283°C at 760 mmHg |
| Flash Point | 134.1°C |
| Vapor Presure | 0.00555mmHg at 25°C |
| Refractive Index | 1.534 |
NSC 9812 - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
NSC 9812 - Nature
Open Data Verified Data
light yellow crystals. Melting point 60 ℃(58 ℃), boiling point 283 ℃,112~115 ℃(0.4kPa), relative density of 1. 1176. Slightly soluble in water, cold ethanol and cold petroleum ether. Soluble in ether, soluble in hot ethanol and hot petroleum ether.
Last Update：2025-06-10 22:55:16
NSC 9812 - Preparation Method
Open Data Verified Data
from p-nitrochlorobenzene and ethanol by etherification reaction. The p-nitrochlorobenzene and ethanol were added to the reaction vessel, the temperature was raised to 82 ° C., ethanol sodium hydroxide solution was added dropwise, and the reaction was carried out at 85-88 ° C. For 3 hours. The alkalinity of the reaction solution was reduced to less than 0.9%, and the temperature was lowered to 75 ° C., and the pH value was adjusted to 6.7~7 with concentrated hydrochloric acid. After standing and stratification, the oil layer is taken out and washed with water to remove sodium nitrophenolate. The oil layer is subjected to vacuum rectification, and the fraction of 214~218 ℃(2. 66~5.32kPa) is taken as the product.
Last Update：2022-01-01 10:50:32
NSC 9812 - Application
Open Data Verified Data
used as an intermediate for drugs and dyes. In medicine for the synthesis of phenacetin.
Last Update：2025-08-19 16:24:40
NSC 9812 - Safety
Open Data Verified Data
- This product is toxic. Inhalation and ingestion are harmful to health. Wear all-protective glasses, wear anti-virus penetration work clothes, and wear self-priming filter compound dust mask when exposed to dust.
- packaging using small opening steel barrel, screw mouth glass bottle, cover pressure mouth glass bottle, plastic bottle or metal barrel (can) outside the wood box. Store in a cool, ventilated warehouse. Keep away from fire and heat source, prevent direct sunlight, and seal the container. Light removal during handling.
Last Update：2025-06-10 22:55:16
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Spot supply
Product Name: 4-Nitrophenetole Visit Supplier Webpage Request for quotationCAS: 100-29-8
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 4-Nitrophenetole Visit Supplier Webpage Request for quotationCAS: 100-29-8
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
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